Single-base Mutation Detection Using Neutravidin-modified Polystyrene Nanoparticle Aggregation
نویسندگان
چکیده
منابع مشابه
Single-base mutation detection using neutravidin-modified polystyrene nanoparticle aggregation.
A single-base mutation assay using the non-crosslinking aggregation of neutravidin-modified polystyrene nanoparticles is described. This method requires only two steps: hybridization of biotinylated probe and sample DNAs, and then mixing with neutravidin-modified nanoparticles. The aggregation was detected within 20 min in total. A combination of the DNA non-crosslinking aggregation and biotin-...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 2004
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.20.893